District of Columbia is about 1,518 times smaller than Colorado.

Colorado is approximately 268,627 sq km, while District of Columbia is approximately 177 sq km, making District of Columbia 0.07% the size of Colorado. Meanwhile, the population of Colorado is ~5.0 million people (4.4 million fewer people live in District of Columbia).
Tip: This to-scale comparison of Colorado vs. District of Columbia uses the Mercator projection, which distorts the size of regions near the poles.