Colorado is about 1,518 times bigger than District of Columbia.

District of Columbia is approximately 177 sq km, while Colorado is approximately 268,627 sq km, making Colorado 151,667% larger than District of Columbia. Meanwhile, the population of District of Columbia is ~601,723 people (4.4 million more people live in Colorado).
Tip: This to-scale comparison of District of Columbia vs. Colorado uses the Mercator projection, which distorts the size of regions near the poles.