District of Columbia is about 1,702 times smaller than Italy.

Italy is approximately 301,340 sq km, while District of Columbia is approximately 177 sq km, making District of Columbia 0.06% the size of Italy. Meanwhile, the population of Italy is ~61.1 million people (60.5 million fewer people live in District of Columbia).
Tip: This to-scale comparison of Italy vs. District of Columbia uses the Mercator projection, which distorts the size of regions near the poles.