Panama is about 426 times bigger than District of Columbia.

District of Columbia is approximately 177 sq km, while Panama is approximately 75,420 sq km, making Panama 42,510% larger than District of Columbia. Meanwhile, the population of District of Columbia is ~601,723 people (3.7 million more people live in Panama).
Tip: This to-scale comparison of District of Columbia vs. Panama uses the Mercator projection, which distorts the size of regions near the poles.
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