Santa Ana is about 17 times smaller than Los Angeles.

Los Angeles (including the city proper only) is approximately 1,215 sq km, while Santa Ana (map shows its 60 named neighbourhoods; the area covers the whole city) is approximately 71 sq km, making Santa Ana 5.84% the size of Los Angeles.
Tip: This to-scale comparison of Los Angeles vs. Santa Ana uses the Mercator projection, which distorts the size of regions near the poles.
Our free app, MapSize by MyLifeElsewhere — compare any two places, to scale on your mobile device.