Fort Wayne is about 14 times smaller than Melbourne.

Melbourne (the 27 councils of metropolitan Melbourne, without the Yarra Ranges, Cardinia, Mornington Peninsula and Nillumbik) is approximately 3,915 sq km, while Fort Wayne (map shows its 315 named neighbourhoods; the area covers the whole city) is approximately 289 sq km, making Fort Wayne 7.39% the size of Melbourne.
Tip: This to-scale comparison of Melbourne vs. Fort Wayne uses the Mercator projection, which distorts the size of regions near the poles.
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