Fort Wayne is about 2.1 times smaller than Madrid.

Madrid is approximately 604 sq km, while Fort Wayne (map shows its 315 named neighbourhoods; the area covers the whole city) is approximately 289 sq km, making Fort Wayne 47.9% the size of Madrid.
Tip: This to-scale comparison of Madrid vs. Fort Wayne uses the Mercator projection, which distorts the size of regions near the poles.
Our free app, MapSize by MyLifeElsewhere — compare any two places, to scale on your mobile device.