Wyoming is about 3.1 times bigger than Maine.

Maine is approximately 79,931 sq km, while Wyoming is approximately 251,489 sq km, making Wyoming 215% larger than Maine. Meanwhile, the population of Maine is ~1.3 million people (764,735 fewer people live in Wyoming).
Tip: This to-scale comparison of Maine vs. Wyoming uses the Mercator projection, which distorts the size of regions near the poles.