Maine is about 3.1 times smaller than Wyoming.

Wyoming is approximately 251,489 sq km, while Maine is approximately 79,931 sq km, making Maine 31.78% the size of Wyoming. Meanwhile, the population of Wyoming is ~563,626 people (764,735 more people live in Maine).
Tip: This to-scale comparison of Wyoming vs. Maine uses the Mercator projection, which distorts the size of regions near the poles.