South Dakota is about 2.5 times bigger than Maine.

Maine is approximately 79,931 sq km, while South Dakota is approximately 196,540 sq km, making South Dakota 146% larger than Maine. Meanwhile, the population of Maine is ~1.3 million people (514,181 fewer people live in South Dakota).
Tip: This to-scale comparison of Maine vs. South Dakota uses the Mercator projection, which distorts the size of regions near the poles.