Maine is about 2.5 times smaller than South Dakota.

South Dakota is approximately 196,540 sq km, while Maine is approximately 79,931 sq km, making Maine 40.67% the size of South Dakota. Meanwhile, the population of South Dakota is ~814,180 people (514,181 more people live in Maine).
Tip: This to-scale comparison of South Dakota vs. Maine uses the Mercator projection, which distorts the size of regions near the poles.