Missouri is around the same size as South Dakota.

South Dakota is approximately 196,540 sq km, while Missouri is approximately 178,414 sq km, making Missouri 90.78% the size of South Dakota. Meanwhile, the population of South Dakota is ~814,180 people (5.2 million more people live in Missouri).
This to-scale comparison of South Dakota vs. Missouri uses the Mercator projection, which distorts the size of regions near the poles. Learn more.

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