Saint Lucia is about 127 times smaller than South Carolina.

South Carolina is approximately 77,983 sq km, while Saint Lucia is approximately 616 sq km, making Saint Lucia 0.79% the size of South Carolina. Meanwhile, the population of South Carolina is ~4.6 million people (4.5 million fewer people live in Saint Lucia).
Tip: This to-scale comparison of South Carolina vs. Saint Lucia uses the Mercator projection, which distorts the size of regions near the poles.