Panama is about 3.3 times smaller than Guinea.

Guinea is approximately 245,857 sq km, while Panama is approximately 75,420 sq km, making Panama 30.68% the size of Guinea. Meanwhile, the population of Guinea is ~15.1 million people (10.5 million fewer people live in Panama).
Tip: This to-scale comparison of Guinea vs. Panama uses the Mercator projection, which distorts the size of regions near the poles.
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