New Mexico is about 11,146 times bigger than Macau.

Macau is approximately 28 sq km, while New Mexico is approximately 314,310 sq km, making New Mexico 1,114,474% larger than Macau. Meanwhile, the population of Macau is ~635,293 people (1.4 million more people live in New Mexico).
Tip: This to-scale comparison of Macau vs. New Mexico uses the Mercator projection, which distorts the size of regions near the poles.