New Mexico is about 4 times bigger than South Carolina.

South Carolina is approximately 77,983 sq km, while New Mexico is approximately 314,310 sq km, making New Mexico 303% larger than South Carolina. Meanwhile, the population of South Carolina is ~4.6 million people (2.6 million fewer people live in New Mexico).
Tip: This to-scale comparison of South Carolina vs. New Mexico uses the Mercator projection, which distorts the size of regions near the poles.
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