Missouri is about 2.4 times bigger than Panama.

Panama is approximately 75,420 sq km, while Missouri is approximately 178,414 sq km, making Missouri 137% larger than Panama. Meanwhile, the population of Panama is ~4.3 million people (1.7 million more people live in Missouri).
This to-scale comparison of Panama vs. Missouri uses the Mercator projection, which distorts the size of regions near the poles. Learn more.

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