Guam is about 2,723 times smaller than Alaska.

Alaska is approximately 1,481,348 sq km, while Guam is approximately 544 sq km, making Guam 0.04% the size of Alaska. Meanwhile, the population of Alaska is ~710,231 people (541,145 fewer people live in Guam).
Tip: This to-scale comparison of Alaska vs. Guam uses the Mercator projection, which distorts the size of regions near the poles.