Alaska is about 2,723 times bigger than Guam.

Guam is approximately 544 sq km, while Alaska is approximately 1,481,348 sq km, making Alaska 272,207% larger than Guam. Meanwhile, the population of Guam is ~169,086 people (541,145 more people live in Alaska).
Tip: This to-scale comparison of Guam vs. Alaska uses the Mercator projection, which distorts the size of regions near the poles.