Colorado is about 3.6 times bigger than Panama.

Panama is approximately 75,420 sq km, while Colorado is approximately 268,627 sq km, making Colorado 256% larger than Panama. Meanwhile, the population of Panama is ~4.3 million people (691,428 more people live in Colorado).
This to-scale comparison of Panama vs. Colorado uses the Mercator projection, which distorts the size of regions near the poles. Learn more.

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