Rome is about 3.5 times bigger than Las Vegas.

Las Vegas (map shows its 26 named neighbourhoods; the area covers the whole city) is approximately 367 sq km, while Rome is approximately 1,287 sq km, making Rome 250% larger than Las Vegas.
Tip: This to-scale comparison of Las Vegas vs. Rome uses the Mercator projection, which distorts the size of regions near the poles.
Our free app, MapSize by MyLifeElsewhere — compare any two places, to scale on your mobile device.