Rome is about 1.6 times bigger than Charlotte.

Charlotte (map shows its 157 named neighbourhoods; the area covers the whole city) is approximately 807 sq km, while Rome is approximately 1,287 sq km, making Rome 60% larger than Charlotte.
Tip: This to-scale comparison of Charlotte vs. Rome uses the Mercator projection, which distorts the size of regions near the poles.
Our free app, MapSize by MyLifeElsewhere — compare any two places, to scale on your mobile device.