Rome is about 6 times bigger than Antwerp.

Antwerp (map shows its 62 named neighbourhoods; the area covers the whole city) is approximately 208 sq km, while Rome is approximately 1,287 sq km, making Rome 518% larger than Antwerp.
Tip: This to-scale comparison of Antwerp vs. Rome uses the Mercator projection, which distorts the size of regions near the poles.
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