Irvine is about 2.3 times smaller than Denver.

Denver is approximately 396 sq km, while Irvine (map shows its 24 named neighbourhoods; the area covers the whole city) is approximately 170 sq km, making Irvine 42.86% the size of Denver.
Tip: This to-scale comparison of Denver vs. Irvine uses the Mercator projection, which distorts the size of regions near the poles.
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