Denver is about 2.3 times bigger than Irvine.

Irvine (map shows its 24 named neighbourhoods; the area covers the whole city) is approximately 170 sq km, while Denver is approximately 396 sq km, making Denver 133% larger than Irvine.
Tip: This to-scale comparison of Irvine vs. Denver uses the Mercator projection, which distorts the size of regions near the poles.
Our free app, MapSize by MyLifeElsewhere — compare any two places, to scale on your mobile device.