Des Moines is about 3.3 times bigger than Boulder.

Boulder is approximately 70 sq km, while Des Moines (map shows its 58 named neighbourhoods; the area covers the whole city) is approximately 228 sq km, making Des Moines 228% larger than Boulder.
Tip: This to-scale comparison of Boulder vs. Des Moines uses the Mercator projection, which distorts the size of regions near the poles.
Our free app, MapSize by MyLifeElsewhere — compare any two places, to scale on your mobile device.