South Carolina is about 1.2 times smaller than Indiana.

Indiana is approximately 92,895 sq km, while South Carolina is approximately 77,983 sq km, making South Carolina 83.95% the size of Indiana. Meanwhile, the population of Indiana is ~6.5 million people (1.9 million fewer people live in South Carolina).
This to-scale comparison of Indiana vs. South Carolina uses the Mercator projection, which distorts the size of regions near the poles. Learn more.

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