Massachusetts is about 41 times bigger than Prague.

Prague is approximately 496 sq km, while Massachusetts is approximately 20,306 sq km, making Massachusetts 3,992% larger than Prague.
Tip: This to-scale comparison of Prague vs. Massachusetts uses the Mercator projection, which distorts the size of regions near the poles.
Our free app, MapSize by MyLifeElsewhere — compare any two places, to scale on your mobile device.