O'Hare Airport is about 4.5 times smaller than Boston.

Boston is approximately 124 sq km, while O'Hare Airport is approximately 27 km² (11 sq mi), making O'Hare Airport 22.08% the size of Boston.
Tip: This to-scale comparison of Boston vs. O'Hare Airport uses the Mercator projection, which distorts the size of regions near the poles.
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