Florida is about 74 times bigger than Lake Okeechobee.

Lake Okeechobee is approximately 1,890 km² (730 sq mi), while Florida is approximately 139,670 sq km, making Florida 7,290% larger than Lake Okeechobee.
Tip: This to-scale comparison of Lake Okeechobee vs. Florida uses the Mercator projection, which distorts the size of regions near the poles.
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