Tennessee is about 111 times bigger than Sao Tome and Principe.

Sao Tome and Principe is approximately 964 sq km, while Tennessee is approximately 106,752 sq km, making Tennessee 10,974% larger than Sao Tome and Principe. Meanwhile, the population of Sao Tome and Principe is ~217,164 people (6.1 million more people live in Tennessee).
Tip: This to-scale comparison of Sao Tome and Principe vs. Tennessee uses the Mercator projection, which distorts the size of regions near the poles.