Senegal is about 2.6 times bigger than Panama.

Panama is approximately 75,420 sq km, while Senegal is approximately 196,722 sq km, making Senegal 161% larger than Panama. Meanwhile, the population of Panama is ~4.3 million people (13.6 million more people live in Senegal).
This to-scale comparison of Panama vs. Senegal uses the Mercator projection, which distorts the size of regions near the poles. Learn more.

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