Sao Tome and Principe is about 646 times smaller than Central African Republic.

Central African Republic is approximately 622,984 sq km, while Sao Tome and Principe is approximately 964 sq km, making Sao Tome and Principe 0.15% the size of Central African Republic. Meanwhile, the population of Central African Republic is ~5.5 million people (5.2 million fewer people live in Sao Tome and Principe).
This to-scale comparison of Central African Republic vs. Sao Tome and Principe uses the Mercator projection, which distorts the size of regions near the poles. Learn more.

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