Saint Lucia is about 122 times smaller than Panama.

Panama is approximately 75,420 sq km, while Saint Lucia is approximately 616 sq km, making Saint Lucia 0.82% the size of Panama. Meanwhile, the population of Panama is ~4.3 million people (4.2 million fewer people live in Saint Lucia).
This to-scale comparison of Panama vs. Saint Lucia uses the Mercator projection, which distorts the size of regions near the poles. Learn more.

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