Papua New Guinea is about 2.6 times bigger than Uruguay.

Uruguay is approximately 176,215 sq km, while Papua New Guinea is approximately 462,840 sq km, making Papua New Guinea 163% larger than Uruguay. Meanwhile, the population of Uruguay is ~3.4 million people (6.2 million more people live in Papua New Guinea).
Tip: This to-scale comparison of Uruguay vs. Papua New Guinea uses the Mercator projection, which distorts the size of regions near the poles.