Ohio is about 406 times bigger than Saint Kitts and Nevis.

Saint Kitts and Nevis is approximately 261 sq km, while Ohio is approximately 106,056 sq km, making Ohio 40,534% larger than Saint Kitts and Nevis. Meanwhile, the population of Saint Kitts and Nevis is ~54,488 people (11.5 million more people live in Ohio).
Tip: This to-scale comparison of Saint Kitts and Nevis vs. Ohio uses the Mercator projection, which distorts the size of regions near the poles.