North Carolina is about 1.7 times bigger than Panama.

Panama is approximately 75,420 sq km, while North Carolina is approximately 126,161 sq km, making North Carolina 67% larger than Panama. Meanwhile, the population of Panama is ~4.3 million people (5.2 million more people live in North Carolina).
This to-scale comparison of Panama vs. North Carolina uses the Mercator projection, which distorts the size of regions near the poles. Learn more.

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