New Orleans is about 2.2 times smaller than Sao Tome and Principe.

Sao Tome and Principe is approximately 964 sq km, while New Orleans is approximately 439 sq km, making New Orleans 45.52% the size of Sao Tome and Principe.
Tip: This to-scale comparison of Sao Tome and Principe vs. New Orleans uses the Mercator projection, which distorts the size of regions near the poles.