New Mexico is about 3,454 times bigger than Anguilla.

Anguilla is approximately 91 sq km, while New Mexico is approximately 314,310 sq km, making New Mexico 345,296% larger than Anguilla. Meanwhile, the population of Anguilla is ~18,741 people (2.0 million more people live in New Mexico).
Tip: This to-scale comparison of Anguilla vs. New Mexico uses the Mercator projection, which distorts the size of regions near the poles.