Mississippi is about 4,673 times bigger than Tuvalu.

Tuvalu is approximately 26 sq km, while Mississippi is approximately 121,489 sq km, making Mississippi 467,165% larger than Tuvalu. Meanwhile, the population of Tuvalu is ~11,544 people (3.0 million more people live in Mississippi).
Tip: This to-scale comparison of Tuvalu vs. Mississippi uses the Mercator projection, which distorts the size of regions near the poles.