Mississippi is about 197 times bigger than Saint Lucia.

Saint Lucia is approximately 616 sq km, while Mississippi is approximately 121,489 sq km, making Mississippi 19,622% larger than Saint Lucia. Meanwhile, the population of Saint Lucia is ~167,122 people (2.8 million more people live in Mississippi).
Tip: This to-scale comparison of Saint Lucia vs. Mississippi uses the Mercator projection, which distorts the size of regions near the poles.