Maryland is about 44 times bigger than Isle of Man.

Isle of Man is approximately 572 sq km, while Maryland is approximately 25,314 sq km, making Maryland 4,326% larger than Isle of Man. Meanwhile, the population of Isle of Man is ~91,382 people (5.7 million more people live in Maryland).
Tip: This to-scale comparison of Isle of Man vs. Maryland uses the Mercator projection, which distorts the size of regions near the poles.