Louisiana is about 183 times bigger than Saint Lucia.

Saint Lucia is approximately 616 sq km, while Louisiana is approximately 112,825 sq km, making Louisiana 18,216% larger than Saint Lucia. Meanwhile, the population of Saint Lucia is ~167,122 people (4.4 million more people live in Louisiana).
Tip: This to-scale comparison of Saint Lucia vs. Louisiana uses the Mercator projection, which distorts the size of regions near the poles.