Isle of Man is about 162 times smaller than Indiana.

Indiana is approximately 92,895 sq km, while Isle of Man is approximately 572 sq km, making Isle of Man 0.62% the size of Indiana. Meanwhile, the population of Indiana is ~6.5 million people (6.4 million fewer people live in Isle of Man).
Tip: This to-scale comparison of Indiana vs. Isle of Man uses the Mercator projection, which distorts the size of regions near the poles.