Honduras is about 1.5 times bigger than Panama.

Panama is approximately 75,420 sq km, while Honduras is approximately 112,090 sq km, making Honduras 49% larger than Panama. Meanwhile, the population of Panama is ~4.3 million people (5.1 million more people live in Honduras).
This to-scale comparison of Panama vs. Honduras uses the Mercator projection, which distorts the size of regions near the poles. Learn more.

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