Guatemala is about 1.4 times bigger than South Carolina.

South Carolina is approximately 77,983 sq km, while Guatemala is approximately 108,889 sq km, making Guatemala 40% larger than South Carolina. Meanwhile, the population of South Carolina is ~4.6 million people (13.1 million more people live in Guatemala).
Tip: This to-scale comparison of South Carolina vs. Guatemala uses the Mercator projection, which distorts the size of regions near the poles.