Spain is approximately 505,370 sq km, while Cuba is approximately 110,860 sq km, making Cuba 21.94% the size of Spain. Meanwhile, the population of Spain is ~50.0 million people (39.0 million fewer people live in Cuba).
This to-scale map shows a size comparison of Spain compared to Cuba. For more details, see an in-depth quality of life comparison of Cuba vs. Spain using our country comparison tool.