Colorado is about 579 times bigger than Northern Mariana Islands.

Northern Mariana Islands is approximately 464 sq km, while Colorado is approximately 268,627 sq km, making Colorado 57,794% larger than Northern Mariana Islands. Meanwhile, the population of Northern Mariana Islands is ~51,475 people (5.0 million more people live in Colorado).
Tip: This to-scale comparison of Northern Mariana Islands vs. Colorado uses the Mercator projection, which distorts the size of regions near the poles.