Colorado is about 7 times bigger than Guinea-Bissau.

Guinea-Bissau is approximately 36,125 sq km, while Colorado is approximately 268,627 sq km, making Colorado 644% larger than Guinea-Bissau. Meanwhile, the population of Guinea-Bissau is ~2.0 million people (3.0 million more people live in Colorado).
Tip: This to-scale comparison of Guinea-Bissau vs. Colorado uses the Mercator projection, which distorts the size of regions near the poles.