Antigua and Barbuda is about 2.5 times bigger than District of Columbia.

District of Columbia is approximately 177 sq km, while Antigua and Barbuda is approximately 443 sq km, making Antigua and Barbuda 150% larger than District of Columbia. Meanwhile, the population of District of Columbia is ~601,723 people (501,388 fewer people live in Antigua and Barbuda).
Tip: This to-scale comparison of District of Columbia vs. Antigua and Barbuda uses the Mercator projection, which distorts the size of regions near the poles.